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CAS NO.:
7331-52-4
Name:
S(-)-3-Hydroxy-gamma-Butyrolactone
Function:

DESCRIPTION
Colorless or light-yellow liquid,soluble in water, alcohol and other organic solvent and insoluble in light petroleum
Molecular Formula
C4H6O3
Structural Formula
Molecular Weight
102.09
SPECIFICATION
 

B
Assay(HPLC)  97% Min 90% Min
Specific Rotation (c=1,EtOH)  -84~-86 -75+5
Opecific Purity(e.e%)  99% Mix 99% Mix
MAIN FUNCTION AND PURPOSE S(-)-3-Hydroxy-- butyrolactone is an important intermediate in organic synthesis and an important chiral pool. It is mainly used in the synthesis of some natural products and some bioactive chiral drugs or antibiotic chiral drugs. For example, it is a key intermediate in synthesis of nerve regulator (R)-GABOB and brain metabolic accelerant S(-)-Oxiracetam. s-3-Hydroxy--butyrolactone can be deoxidized to S(-)-3-hydroxy-tetrahydrofurane which is an important intermediate of anti-AIDS drugs. It is also used in the synthesis of S(-)-3-hydroxy-4-bromobutyric acid which is a potential stabilizer. It can also be used to produce S(-)-5-hydroxymethyl-oxazolin which is a new antibiotic drug. Besides, both S(-)-N-methyl-hydroxypyrrole and (R)-N-methyl-3-methylamino-pyrrole have important bioactivity, and they can be made from s-3-Hydroxy--butyrolactone by simple reaction. Furthermore, s-3-Hydroxy--butyrolactone can synthesize many natural products.
PACKING
in 25kg or 200kg drum or according to customer requirement
STORAGE
Kept airtightly in a light-proof, dry and cool place.


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